Named after the exhibition grounds (Messe) and the central bus station (ZOB).
Until June 2002 the station was called Witzleben; it was then renamed Messe Nord/ICC after the nearby Internationales Congress Centrum, opened in 1979. Since 15 December 2024 it has been Messe Nord/ZOB, after the Zentraler Omnibusbahnhof about 300 metres away, Berlin’s long-distance coach station, in service since 1966.