'Ickenham' means the homestead or village of a man called Tic(c)a.
The Domesday Book of 1086 records it three times as Ticheham. The T was lost in the 13th–14th centuries through confusion with the Middle English word for 'at'. The form Tickenham survived until the 19th century for an area lying partly in Hillingdon and partly in Ickenham. The station opened in 1905 as Ickenham Halt.