‘Uxbridge’ means Wixan’s Bridge, after an Anglo-Saxon tribe.
The Wixan, a 7th-century Saxon tribe from Lincolnshire, also settled in what became Middlesex; Uxendon (‘Wixan’s Hill’) and Waxlow (‘Wixan’s Wood’) bear their name too. The bridge crossed the River Colne near the bottom of Oxford Road, where a modern road bridge stands. Uxbridge is not in Domesday Book but appears in 1107 as Woxbrigge.