Named after the direction it leads: to Hohenschönhausen.
Named in 1885, first as Hohen-Schönhausener Straße, the street was part of the old road from Berlin to the village of Hohenschönhausen. It already appears on the Hobrecht Plan, a development plan for Berlin, as ‘Straße 39’. Until the 1970s it had only one carriageway, with the tram running along the side.