Named after the villages of Chalfont and Latimer.
The Domesday Book of 1086 lists the Chalfonts as Celfunte, likely from Old English cealc funta, chalk stream or chalk spring. Latimer, once joined with Chenies under the name Isenhampstead, recalls William Latimer, who came into possession of the manor in 1326. The station opened in 1889 as Chalfont Road and was renamed in 1915; the village that grew round it became Little Chalfont in 1925.